Tamoxifen male

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    Tamoxifen male


    It is intended for general informational purposes only and does not address individual circumstances. It is not a substitute for professional medical advice, diagnosis or treatment and should not be relied on to make decisions about your health. Never ignore professional medical advice in seeking treatment because of something you have read on the Web MD Site. If you think you may have a medical emergency, immediately call your doctor or dial 911. Pubertal gynaecomastia affects up to 70% of male adolescents, with the highest prevalence occurring at 14 years of age. While spontaneous regression occurs in 90% of cases within three years, until then, symptoms of mastodynia and psychological distress are prevalent in some patients prior to surgical treatment. Tamoxifen, a selective oestrogen receptor modulator (SERM), given at 20 mg daily for six months, was found to be a safe, well-tolerated and effective alternative treatment to current therapeutic options of watchful waiting (no management) and invasive cosmetic surgery. No adverse effects were observed in hormonal and auxological studies. The patient presented was able to avoid undergoing surgery, which should be reserved for persistent gynaecomastia present at the end of puberty after failing a trial of tamoxifen. Randomised controlled trials (RCTs) are needed for definitive therapeutic recommendations.

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    Andrology. 2016 Sep;45776-88. doi 10.1111/andr.12197. Epub 2016 May 6. Tamoxifen in men a review of adverse events. Wibowo E1, Pollock PA1. Tamoxifen is used for hormone-dependent types of breast cancer. It works by blocking the effect of estrogen in the body and thus stopping the growth of cancer cells that possess the estrogen receptors. Tamoxifen must be taken every day for the duration of antiandrogen treatment. In one study, only 8 percent of men who took an antiandrogen plus tamoxifen developed gynecomastia compared with 68 percent of men who took the antiandrogen alone. Tamoxifen may also be given to men who develop gynecomastia while taking antiandrogens.

    Hormone therapy (sometimes called endocrine therapy) is a way to treat cancer by using hormones or drugs or other treatments that affect hormones. Hormone therapy is a form of systemic therapy, like chemotherapy. It can be used after surgery (adjuvant therapy) to help lower the risk of cancer coming back, or before surgery (neoadjuvant treatment). It is also used to treat cancer that has spread, or cancer that has come back after treatment (recurred). Some breast cancers grow in response to the hormones estrogen or progesterone. Estrogen and progesterone are usually thought of as female hormones, but men have them in their bodies also, just at lower levels. About 9 of 10 breast cancers in men are hormone receptor-positive. Most male breast cancer is hormone dependent, via estrogen (ER/PR positive i.e. estrogen receptor, progesterone receptor positive). This is, on the whole, good news as it means the cancer cells are dependent (at least initially) on a signal coming from estrogen via its receptor for survival. Cut that off, and the cells mostly die, or at least become dormant. This is why for many men with breast cancer hormone therapy is the most effective part of their treatment plan. That means we get Tamoxifen, as there is no data in support of other types of hormone therapy (actually there is little data either way as I have discussed in another post). That Tamoxifen has side effects is widely known, especially for women, because larger studies have been done for them on this subject. For men there is less evidence available, and Wibowo and colleagues have done a great service in pulling together what there is to survey the situation of Tamoxifen complications for men.

    Tamoxifen male

    Tamoxifen in men a review of adverse events shows its mostly well., Tamoxifen and Male Infertility - Reviews - Treato

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  3. Tamoxifen is a drug called an estrogen receptor antagonist, which works by blocking the receptor so that estrogen can’t work its usual effects within the body. Other Uses of Tamoxifen.

    • Other Uses of Tamoxifen - News Medical.
    • UpToDate.
    • Hormone Therapy for Breast Cancer in Men.

    Issues With Using Tamoxifen For Bodybuilding. where we now have high estrogen levels in the body and with nothing to stop this estrogen from causing gyno in male. Another use is tamoxifen for men who take anabolic steroids, in order to block the large amounts of estrogen produced by their bodies once they stop taking them. One of the primary uses of tamoxifen for men is the treatment of breast cancer. Pubertal gynaecomastia affects up to 70% of male adolescents, with the highest prevalence occurring at 14 years of age. While spontaneous regression occurs.

     
  4. zigor Well-Known Member

    Selected from data included with permission and copyrighted by First Databank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, expect as may be authorized by the applicable terms of use. CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment. Finasteride and sexual side effects - NCBI - NIH Finasteride Propecia Side Effects, Dosage & Results Propecia, Proscar New Sexual Dysfunction Warnings - WebMD
     
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