Zoloft (sertraline) is a selective serotonin reuptake inhibitor (SSRI) which helps correct the imbalance of serotonin in the brain. Zoloft is commonly prescribed for depression, panic disorder, obsessive-compulsive disorder (OCD), and post-traumatic stress disorder (PTSD). However, it can also be given to IBS patients, usually in lower doses than those given to depressed patients. The most common side effects of Zoloft are constipation, anxiety, dizziness, drowsiness, dry mouth, loss of appetite, nausea, stomach upset and vomiting. I was diagnosed with IBS when I was 18 after three months of horrible tests and dead ends. I was reluctant to accept the diagnosis, but I had spent the last three months in bed with cramps, nausea, diarrhea and constipation and I had become very depressed (although I was in denial about my depression). My doctor prescribed 50mg of Zoloft (half a tablet first, then a full 50mg). I was still hesitant but went with the regimen, and within a month I was back to normal, started college, got engaged, and moved to a new house. You might be wondering why your doctor would prescribe an antidepressant for your irritable bowel syndrome (IBS) if you are not depressed. Or, perhaps like many IBS sufferers, you do suffer from depression or anxiety alongside your IBS, so the idea makes a little more sense, but you are curious as to what effects an antidepressant might have on your IBS symptoms. The following overview will answer the question of why antidepressants are sometimes used as a treatment for IBS and educate you as to the types of antidepressants that are commonly prescribed to IBS patients. Although medications in this class are labeled as antidepressants, they have effects that go beyond stabilizing a depressed mood. Antidepressants have been shown to reduce anxiety and pain sensations while having positive effects on the digestive system. Physicians may prescribe an antidepressant to an IBS patient, but this is considered an "off-label" use of the drug, as no antidepressant has received FDA approval as an IBS treatment. However, the American College of Gastroenterology, after an extensive research review, concluded that there is enough research support on the effectiveness of two classes of drugs – TCAs and SSRIs – to recommend their use in treating IBS. Sildenafil for ed Viagra with food Amoxil generic Day 5 on sertraline and the majority of the side effects are settling. Slept last night woke up this morning and thought, need to get some structure. So up dressed and ready. Still not 100% but I can manage the other symptoms as they are similar to IBS. Now going to plan on slowly building myself back up. Thank you everyone for your support. Low doses of IBS-effective Antidepressants can raise the pain threshold for the painful abdominal cramps of Irritable Bowel Syndrome, and they can also either increase or decrease depending upon the class of drug the rate of gastrointestinal contractions as well, thus altering bowel function in either direction and helping diarrhea or. Studies have shown that antidepressants in low doses can be effective in treating the symptoms of IBS. Using antidepressants for IBS is considered an off-label approach to treating the symptoms of. As far as scientists know, irritable bowel syndrome doesn't cause depression, and depression doesn’t cause IBS. Sometimes, one condition can make the other one worse. At the same time, treatments that usually relieve the mood disorder can help some people with their IBS symptoms, too. They can give you even more options to consider when you’re looking for relief. The symptoms of irritable bowel syndrome can cause a level of distress that looks like depression. Some people are so worried that their diarrhea, constipation, or other symptoms will flare up that they avoid going to work, school, or out with friends. On the other hand, the mood disorder may influence the way people handle IBS. They may focus less on their social lives and lose interest in activities they once enjoyed. They may feel too tired or hopeless to bother changing their diet to ease digestive symptoms or think they can't treat their constipation or diarrhea well enough. Some depression meds can treat the mood disorder and some of the symptoms of IBS. But they're used in different ways for each condition, so it's important to talk with your doctor to learn how you should take them. Even people with irritable bowel syndrome who aren’t depressed can get relief from antidepressants. Antidepressants are commonly used as a treatment option for patients with irritable bowel syndrome with diarrhea (IBS-D). Some antidepressants for IBS have also shown to be effective at low doses in IBS patients with constipation (IBS-C). In addition to the disturbances in intestinal motility (resulting in either diarrhea or constipation) and abdominal pain that are experienced by patients with IBS, recent studies have also shown that the normal function of the brain being able to “turn down” pain signals sent from the gut is impaired. The pain can become severe when the patient is experiencing emotional distress, which may occur due to stresses in life or due to the stress and frustration of IBS symptoms. Antidepressants can help the brain-gut dysfunction of IBS. Tricyclic antidepressants (TCAs) work by affecting the naturally occurring chemical messengers, called neurotransmitters, in the brain and body. TCAs block the absorption (or reuptake) of the neurotransmitters serotonin and norepinephrine. Sertraline for ibs Antidepressants for IBS - Irritable Bowel Syndrome Home Page, Irritable Bowel Syndrome IBS Medications - HelpForIBS Xanax 3720Prednisone and pregnancyCiprofloxacin for diverticulitis Selective serotonin reuptake inhibitor antidepressants seem to promote global well being in some patients with irritable bowel syndrome and, possibly, some. How do SSRIs help patients with irritable bowel syndrome?. Can antidepressants treat your IBS? Health24. The Treatment of Irritable Bowel Syndrome - NCBI - NIH. I was on Sertraline for while and developed I have IBS-D and developed near semi-incontinence and 'follow through' about a year after I started taking them. It comes up in a Google search if you look for it. Instead of the normal muscular activity motility of digestion, IBS patients may experience. Why are antidepressants used to treat IBS. Sertraline Zoloft. So, antidepressant medications were proposed to treat IBS with long lasting effect. This study aimed to compare effect of sertraline to placebo in treatment of IBS.