The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. A secondary aim is to determine whether certain patient features will predict response to sertraline, naltrexone or the combination of the two drugs. Listing a study does not mean it has been evaluated by the U. Subjects will be randomized into treatment groups for 14 weeks. This study will examine depressed alcoholic outpatients to assess whether combining naltrexone (Revia) and sertraline (Zoloft) will result in greater reductions in both drinking and depression over either medication alone or placebo. The followup phase includes two visits at 6 and 9 months after treatment. The proposed study will examine managing relapse in patients with alcohol dependence and depression using a 14-week double-blind, placebo-controlled, combination of 100 mg/day of naltrexone, 200 mg/day of sertraline, and individual, cognitive behavioral therapy (CBT). For testing the medication, the design will be 2x2, consisting of four groups: naltrexone/sertraline, naltrexone only, sertraline only, placebo. All four groups will receive once weekly sessions of CBT given by therapists experienced in working with patients with substance disorders and trained in the principles of CBT. Don't stop taking an antidepressant or other medication just so that you can drink. Most antidepressants require taking a consistent, daily dose to maintain a constant level in your system and work as intended. Stopping and starting your medications can make your depression worse. While it's generally best not to drink at all if you're depressed, ask your doctor. If you have depression: If you're concerned about your alcohol use, you may benefit from substance abuse counseling and treatment programs that can help you overcome your misuse of alcohol. Joining a support group or a 12-step program such as Alcoholics Anonymous may help. If you're at low risk of addiction to alcohol, it may be OK to have an occasional drink, depending on your particular situation, but talk with your doctor. Sildenafil definition Cialis generic us Does amoxicillin make you tired This study will examine depressed alcoholic outpatients to assess whether combining naltrexone Revia and sertraline Zoloft will result in greater reductions in. Alcohol can increase the nervous system side effects of sertraline such as dizziness, drowsiness, and difficulty concentrating. Some people may also experience impairment in thinking and judgment. Talk to your doctor or pharmacist if you have any questions or concerns. Alcohol avoid alcohol while you are taking sertraline, especially when you first start treatment. Drinking alcohol while taking SSRIs can cause. Sertraline is a type of antidepressant known as a selective serotonin reuptake inhibitor (SSRI). It's often used to treat depression, and also sometimes panic attacks, obsessive compulsive disorder (OCD) and post-traumatic stress disorder (PTSD). Sertraline helps many people recover from depression, and has fewer unwanted side effects than older antidepressants. Sertraline comes as tablets, which are available only on prescription. Sertraline can be taken by adults for depression or obsessive compulsive disorder. Sertraline can be taken by children aged 6 to 17, but only for obsessive compulsive disorder. Check with your doctor before starting to take sertraline if you: If you have diabetes, sertraline can make it more difficult to keep your blood sugar stable. You can choose to take sertraline at any time, as long as you stick to the same time every day. You should avoid or limit the use of alcohol while being treated with sertraline. Alcohol can increase the nervous system side effects of sertraline such as dizziness, drowsiness, and difficulty concentrating. Some people may also experience impairment in thinking and judgment. Talk to your doctor or pharmacist if you have any questions or concerns. Sertraline alcohol Zoloft and Alcohol The Combination is Growing - The Cabin., Sertraline and Alcohol / Food Interactions - Que es doxycycline hyclate Alcohol can also cause sedation and may enhance these effects from Zoloft. That means if you mix alcohol and Zoloft, you may experience the drowsy effects more quickly than someone who drinks the. Can I Mix Zoloft and Alcohol? - Healthline. Sertraline Health Navigator NZ. Sertraline an antidepressant - NHS. Zoloft, and the other anti-depressants like it, can also produce sedative effects. Since alcohol is a central nervous system depressant, lowered heart rate and blood pressure changes are possible. This becomes even more likely as the quantity of alcohol consumed increases. Read all of this leaflet carefully before you start taking this medicine because it contains important information for you. - Keep this may need to read It's best to avoid combining antidepressants and alcohol. It may worsen your symptoms, and it can be dangerous. If you mix antidepressants and alcohol.