Sildenafil citrate is the active ingredient in Sildenafil Citrate 50 MG Tablet, which is informally also known as the "blue pill". It is primarily used for the treatment of erectile dysfunction (ED), which is also called impotence, in men. Erectile dysfunction is a condition where a man is unable to achieve and/or maintain a penile erection adequate enough for sexual intercourse. It happens when there is a decreased blood flow to the penis. The decreased blood flow may be due to physical complications following an injury or disease or due to some psychological conditions such as anxiety, stress, depression, etc. Chronic lifestyle factors such as obesity, smoking, drinking, etc., could also contribute to ED. ED is strongly age-related, and the occurrence of moderate-to-severe ED could increase two-fold to three-fold between the ages of 40 and 70 years. 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Men between the ages of 30 and 65 would be eligible to buy four tablets after a consultation with a pharmacist. In 2017, the Medicines and. Sildenafil relaxes muscles of the blood vessels and increases blood flow to particular areas of the body. Sildenafil under the name Viagra is used to treat erectile dysfunction (impotence) in men. Another brand of sildenafil is Revatio, which is used to treat pulmonary arterial hypertension and improve exercise capacity in men and women. Do not take sildenafil if you are also using a nitrate drug for chest pain or heart problems, including nitroglycerin, isosorbide dinitrate, isosorbide mononitrate, and some recreational drugs such as "poppers". Taking sildenafil with a nitrate medicine can cause a sudden and serious decrease in blood pressure. Some medicines can cause unwanted or dangerous effects when used with sildenafil. Tell your doctor about all your current medicines, especially riociguat (Adempas). Contact your doctor or seek emergency medical attention if your erection is painful or lasts longer than 4 hours. A prolonged erection (priapism) can damage the penis. The recommended dose is 50 mg taken as needed approximately one hour before sexual activity. Based on efficacy and tolerability, the dose may be increased to 100 mg or decreased to 25 mg. The maximum recommended dosing frequency is once per day. If Sildenafil is taken with food, the onset of activity may be delayed compared to the fasted state (see section 5.2). Since sildenafil clearance is reduced in patients with hepatic impairment (e.g. Based on efficacy and tolerability, the dose may be increased step-wise to 50 mg up to 100 mg as necessary. With the exception of ritonavir for which co-administration with sildenafil is not advised (see section 4.4) a starting dose of 25 mg should be considered in patients receiving concomitant treatment with CYP3A4 inhibitors (see section 4.5). 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