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    An unpublished study finished in 2000 indicated increased cardiac risks associated with Celebrex. D., Director, Public Citizen's Health Research Group In January, Public Citizen petitioned to have Bextra and Celebrex, two COX-2 inhibitors, removed from the market because they increase the risk of heart attacks. While we are pleased that the FDA has taken Bextra off the market, it has recklessly allowed Celebrex to continue to be sold. Food and Drug Administration (FDA) has called on Pfizer to pull Bextra from the shelves and place a warning on Celebrex. Last year, almost twice as many prescriptions were written for Celebrex as for Bextra - 23.9 million prescriptions compared to 12.9 million. Neither Bextra nor Celebrex protects the gastrointestinal tract as drugmakers claim. Given that neither drug has any unique benefits but both carry unique cardiac risks, it is unconscionable to leave Celebrex on the market. In addition, the FDA is sowing dangerous confusion by requiring all nonsteroidal anti-inflammatory drugs (NSAIDs) - Celebrex and all non-aspirin NSAIDs - to warn about increased cardiac risks, even though the risks of Celebrex are clearly higher than at least one NSAID, naproxen. Is a non-steroidal anti-inflammatory drug (NSAID) used in the treatment of osteoarthritis, rheumatoid arthritis, acute pain, painful menstruation and menstrual symptoms, and is also used to reduce numbers of colon and rectum polyps in patients with familial adenomatous polyposis. By inhibiting prostaglandin synthesis, non-steroidal anti-inflammatory drugs (NSAIDs) cause mucosal damage, ulceration and ulcer complication throughout the gastrointestinal tract.

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