Tamoxifen use in males

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    Tamoxifen use in males


    Reggie Johal is the founder of Predator Nutrition, a UK based health and supplement store. Reggie owes much of his extensive strength and fitness knowledge to his former career as a Great Britain American Footballer. About half of male breast cancer patients who take the drug tamoxifen to prevent their disease from returning report side effects such as weight gain and sexual dysfunction, which prompts more than 20 percent of them to discontinue treatment, according to researchers at The University of Texas MD Anderson Cancer Center. The study, which is the largest to date of how the estrogen-blocking drug is tolerated in men with breast cancer, was published today in the journal Annals of Oncology."While tamoxifen is effective in treating breast cancer in men, little is known about its toxicity," said Sharon Giordano, M. D., associate professor of medicine in MD Anderson's Department of Breast Medical Oncology and senior author of the study. "This research will help doctors and patients better understand the side effects men experience. With this information, patients can make more informed decisions about treatment risks and benefits."Few Empirical Studies of Rare Disease Only about 2,000 men are diagnosed with breast cancer in the United States each year, but its incidence is increasing. Since the disease is so rare, little published evidence exists to guide treatment decisions, and most are based on what works in women. There is limited data about the toxicity of anti-hormonal treatments in men.

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    About half of male breast cancer patients who take the drug tamoxifen to prevent their disease from returning report side effects such as weight. The study also found a 22% rise in the numbers using tamoxifen, and the chief researcher, Professor Bruce Davis, discovered that male. The hormonal treatment that is most commonly prescribed to men is tamoxifen, but some men also have used other drugs known as aromatase inhibitors e.g.

    Tamoxifen is a drug called an estrogen receptor antagonist, which works by blocking the receptor so that estrogen can’t work its usual effects within the body. Estrogen is an important hormone in the female body and plays a big role in some types of breast cancer. As a result, tamoxifen is commonly used to prevent breast cancer from appearing or coming back in women who are at a high risk of or have a history of breast cancer. This is not the only way that tamoxifen can be used, however, and there are several alternative ways that this drug can be used to offer a benefit. The following information goes into more detail about alternative uses of the medication and how it can be used. Some individuals that experience premature puberty may notice symptoms of Mc Cune-Albright syndrome, such as bone disfiguration and skin discoloration. Tamoxifen can be used to decrease the rate of bone maturation and alter the predicted adult height, which is usually lower in those with premature puberty. While estrogen is often a hormone more associated with women, there are several reasons why tamoxifen, a drug used to block the effects of estrogen, may be used to treat men. Men who get breast cancer are often treated with a course of tamoxifen. It can also be useful to stop or reverse a condition called gynecomastia, where the breast tissue of adolescent boys or men grows and sometimes becomes uncomfortable. Another use is tamoxifen for men who take anabolic steroids, in order to block the large amounts of estrogen produced by their bodies once they stop taking them. One of the primary uses of tamoxifen for men is the treatment of breast cancer. While this type of cancer is fairly rare in men, the type that most men get involves tumors that are estrogen receptor-positive, meaning that estrogen encourages their growth. Since tamoxifen is a selective estrogen receptor modulator, or SERM, it helps to keep estrogen from binding to the proteins on these tumors and therefore inhibits their growth.

    Tamoxifen use in males

    Does tamoxifen produce side effects in men? - WebMD, Gymgoers 'are abusing tamoxifen' Society The Guardian

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  5. Similar to the use of clomiphene, tamoxiphen has been used to treat low testosterone and low sperm counts infertility in males. Adverse effects of tamoxifen.

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    While tamoxifen is effective in treating breast cancer in men, little is known about its toxicity," said Sharon Giordano, M. D. associate professor of medicine in MD Anderson's Department of Breast Medical Oncology and senior author of the study. Other Uses of Tamoxifen. which then led to come concern about the use of tamoxifen in young humans. H-RT should be the standard of care for men with low risk prostate cancer, study shows. Issues With Using Tamoxifen For Bodybuilding We get an almost daily question which asks us what we suggest for PCT, and how the person in question has been told by everybody they must use a prescription breast cancer drug called Tamoxifen, to ensure they retain their muscle gains and prevent potential problems with gynecomastia.

     
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    In order to use Medscape, your browser must be set to accept cookies delivered by the Medscape site. Medscape uses cookies to customize the site based on the information we collect at registration. The cookies contain no personally identifiable information and have no effect once you leave the Medscape site. Er +, tamoxifen and hysterectomy anyone? Cancer Survivors. Tamoxifen after total hysterectomy and ovary removal OncoLink Italian Randomized Trial Among Women With Hysterectomy.
     
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