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Discussion in 'Canadian Pharmacies' started by Name, 01-Jan-2020.

  1. North_Star Guest

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  8. Kai+ Guest

    Inpatient therapy with parenteral antibiotics is recommended for patients with associated SIRS, hemodynamic instability, and/or mental status changes. Poor compliance, failure to respond to oral antibiotics, facial involvement, and immune suppression are additional indications for inpatient parenteral therapy until the patient is stable and improving. The initial antibiotic selection should cover MRSA for patients with coexisting penetrating and/or surgical trauma, evidence of MRSA infection elsewhere, known nasal MRSA colonization, and intravenous drug abuse. Coverage should also take into consideration the prevalence of MRSA in the patient’s hospital and community. Once microorganisms are identified based on cultures, treatment is tailored to the patient’s needs. The most common offenders (beta-hemolytic streptococci, MSSA, MRSA) are discussed in Cellulitis Organism-Specific Therapy. Similarly, empiric therapy in patients with cellulitis involving specific clinical situations (ie, marine exposure, fresh water exposure, nonhuman mammalian bites, human bites, diabetic foot wounds, recurrent cellulitis, facial cellulitis/erysipelas/periorbital cellulitis, surgical site infections, immunosuppressive states, necrotizing cellulitis/Fournier gangrene) is beyond the scope of this article. Doxycycline for cellulitis - MedHelp Cellulitis in the face of antibiotic resistance - Page 2 of 2 - Clinical. Medications for Cellulitis Doxycycline, Keflex, Bactrim.
     
  9. WinssentKrauch1963 Moderator

    Wyeth Pharmaceuticals is heavily promoting Effexor XR for the treatment of depression and Generalized Anxiety Disorder (GAD), and the gist of the promotion is that Effexor XR is more powerful at producing remission than the SSRIs. Even if it is believable, how should this influence our prescribing decisions? As practitioners, we have all been bombarded by the Effexor promotional literature, with slogans such as: “THE GOAL IS REMISSION OF SYMPTOMS” and “LET’S GET IT RIGHT THE FIRST TIME.” These are hardly news flashes to psychiatrists, and the implication that we don’t already try our darndest to get our patients all the way well is mildly insulting. Of course, we all know where Wyeth is coming from here. They are trying to convince us to think in terms of “remission” (Ham-D depression scale 7 or less) rather than “response” (Ham-D 50% improved) because Effexor XR claims to be better than the SSRIs at bringing about remission, but not at producing response. Let’s look at the basis for Wyeth’s claim, which is the now famous study published in the British Journal of Psychiatry in 2001 by Thase et al (1) showing that Effexor’s remission rates were 45% (vs. The study had excellent methodology, comprising a pooled analysis of all the data the company had collected comparing Effexor with Prozac, Paxil, and Luvox. By psychiatric research standards, the numbers were huge: 851 patients in the Effexor XR group, 748 in the SSRI group (Prozac, Paxil, and Luvox), and 446 in the placebo group. The doses of comparator SSRIs were robust enough to mirror what we actually use in clinical practice, and treatment duration was reasonable, between 6 and 8 weeks. Best Antidepressant for Anxiety - Consumer Reports Effexor XR vs. Zoloft for GAD - Anxiety - MedHelp Zoloft vs. Effexor Differences & Side Effects - RxList
     
  10. Holand Guest

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