Janumet contains a combination of metformin and sitagliptin. Metformin and sitagliptin are oral diabetes medicines that help control blood sugar levels. Metformin works by decreasing glucose (sugar) production in the liver and decreasing absorption of glucose by the intestines. Sitagliptin works by regulating the levels of insulin your body produces after eating. Janumet is used together with diet and exercise to improve blood sugar control in adults with type 2 diabetes mellitus. You should not use Janumet if you have severe kidney disease or diabetic ketoacidosis (call your doctor for treatment with insulin). Janumet may cause a serious condition called lactic acidosis.');"lactic acidosis. Get emergency medical help if you have even mild symptoms such as: muscle pain or weakness, numb or cold feeling in your arms and legs, trouble breathing, stomach pain, nausea with vomiting, slow or uneven heart rate, dizziness, or feeling very weak or tired. Rarely, too much metformin can build up in the body and cause a serious (sometimes fatal) condition called lactic acidosis. Lactic acidosis is more likely if you are an older adult, if you have kidney or liver disease, dehydration, heart failure, heavy alcohol use, if you have surgery, if you have X-ray or scanning procedures that use iodinated contrast, or if you are using certain drugs. Sitagliptin works by increasing levels of natural substances called incretins. For some conditions, your doctor may tell you to stop taking this medication for a short time. Stop taking this medication and get medical help right away if you have any symptoms of lactic acidosis, such as unusual tiredness, dizziness, severe drowsiness, chills, blue/cold skin, muscle pain, fast/difficult breathing, slow/irregular heartbeat, or stomach pain with nausea/vomiting/diarrhea. Show More This combination medication is used with a proper diet and exercise program and possibly with other medications to control high blood sugar. Incretins help to control blood sugar by increasing insulin release, especially after a meal. They also decrease the amount of sugar your liver makes. Metformin works by helping to restore your body's proper response to the insulin you naturally produce. It also decreases the amount of sugar that your liver makes and that your stomach/intestines absorb. Controlling high blood sugar helps prevent kidney damage, blindness, nerve problems, loss of limbs, and sexual function problems. Metoprolol xl dose Where to buy flagyl for cats Learn about JANUMET® sitagliptin and metformin HCl tablets and type 2 diabetes therapy. Janumet is a combination of two drugs, metformin and sitagliptin, that are used for reducing blood glucose sugar levels in individuals with type 2 diabetes. Inadequately controlled on sitagliptin alone. 1000 mg/day metformin PO plus 100 mg/day PO sitagliptin. Not to exceed daily PO dose of 2,000 mg of metformin or 100 mg or sitagliptin. Do not administer to patients 80 years before assessing renal function and determined to be normal Can be used along with diet and exercise to lower blood sugar in adults with type 2 diabetes. Make sure you take the medicine exactly as your doctor tells you to. Should not be used in patients with type 1 diabetes or with diabetic ketoacidosis (increased ketones in the blood or urine). If you have had pancreatitis (inflammation of the pancreas), it is not known if you have a higher chance of getting it while taking work to help lower blood sugar. You will also find tools to track your progress and other resources to help you ask the questions that are important to you at your next doctor appointment. Also, check out Steps to Diabetes Goals, a program that provides information on type 2 diabetes, including tips and tools that you may find useful. Metformin janumet JANUMET® XR sitagliptin and metformin HCl extended-release., Metformin and sitagliptin Janumet Drug Facts, Side Effects and Dosing Cytotec canada Compare Janumet vs. Metformin, which is better for uses like Type 2 Diabetes. Compare head-to-head ratings, side effects, warnings, dosages, interactions and patient reviews. Patients rated Metformin 3.2/5 over Janumet 3.1/5 in overall satisfaction. Compare Janumet vs Metformin - Treato. Janumet, Janjumet XR metformin-sitagliptin dosing, indications.. HIGHLIGHTS OF PRESCRIBING INFORMATION Heart failure has been observed.. JANUMET is a prescription medicine that contains two prescription diabetes medicines, sitagliptin JANUVIA® and metformin. JANUMET can be used along. Metformin/sitagliptin Janumet is an expensive drug used to treat type 2 medicine lowers blood sugar. This drug is more popular than comparable drugs. A generic form of Janumet may become available in 2027. Metformin and sitagliptin combination is used to treat high blood sugar levels caused by type 2 diabetes. Metformin reduces the absorption of sugar from the stomach, reduces the release of stored sugar from the liver, and helps your body use sugar better.