500 mg PO once, then 250 mg once daily for 4 days 2 g extended release suspension PO once 500 mg IV as single dose for at least 2 days; follow with oral therapy with single dose of 500 mg to complete 7-10 days course of therapy Infection of pharynx, cervix, urethra, or rectum: Ceftriaxone 250 mg IM once plus azithromycin 1 g PO once (preferred) or alternatively doxycycline 100 mg PO q12hr for 7 days CDC STD guidelines: MMWR Recomm Rep. June 5, 20(RR3);1-137 Agitation Allergic reaction Anemia Anorexia Candidiasis Chest pain Conjunctivitis Constipation Dermatitis (fungal) Dizziness Eczema Edema Enteritis Facial edema Fatigue Gastritis Headache Hyperkinesia Hypotension Increased cough Insomnia Leukopenia Malaise Melena Mucositis Nervousness Oral candidiasis Pain Palpitations Pharyngitis Pleural effusion Pruritus Pseudomembranous colitis Rash Rhinitis Seizures Somnolence Urticaria Vertigo Anaphylaxis Angioedema Anorexia Bronchospasm Constipation Dermatologic reactions Dyspepsia Elevated liver enzymes Erythema multiforme Flatulence Oral candidiasis Pancreatitis Pseudomembranous colitis Pyloric stenosis, rare reports of tongue discoloration Stevens-Johnson syndrome Torsades de pointes Toxic epidermal necrolysis Vomiting/diarrhea, rarely resulting in dehydration Neutropenia Elevated bilirubin, AST, ALT, BUN, creatinine Alterations in potassium Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) Use with caution in abnormal liver function, hepatitis, cholestatic jaundice, hepatic necrosis, and hepatic failure have been reported, some of which have resulted in death; discontinue azithromycin immediately if signs and symptoms of hepatitis occur Injection-site reactions can occur with IV route In treatment of gonorrhea or syphilis, perform susceptibility culture tests before initiating azithromycin therapy; may mask or delay symptoms of incubating gonorrhea or syphilis. Bacterial or fungal superinfection may result from prolonged use Prolonged QT interval: Cases of torsades de pointes have been reported during postmarketing surveillance; use with caution in patients with known QT prolongation, history of torsades de pointes, congenital long QT syndrome, bradyarrhythmias, or uncompensated heart failure; also use with caution if coadministering with drugs that prolong QT interval or proarrhythmic conditions (eg, hypokalemia, hypomagnesemia); elderly patients may be more susceptible to drug-associated effects on QT interval Pneumonia: PO azithromycin is safe and effective only for community-acquired pneumonia (CAP) due to C pneumoniae, H influenzae, M pneumoniae, or S pneumoniae Cases of Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) reported; despite successful symptomatic treatment of allergic symptoms, when symptomatic therapy was discontinued, allergic symptoms recurred soon thereafter in some patients without further azithromycin exposure; if allergic reaction occurs, the drug should be discontinued and appropriate therapy instituted; physicians should be aware that allergic symptoms may reappear when symptomatic therapy discontinued Endocarditis prophylaxis: Indicated only for high-risk patients, per current AHA guidelines Use caution in renal impairment (Cr Cl Because of the low levels of azithromycin in breastmilk and use in infants in higher doses, it would not be expected to cause adverse effects in breastfed infants (Lact Med; https://nih.gov/newtoxnet/lactmed.htm) Binds to 50S ribosomal subunit of susceptible microorganisms and blocks dissociation of peptidyl t RNA from ribosomes, causing RNA-dependent protein synthesis to arrest; does not affect nucleic acid synthesis Concentrates in phagocytes and fibroblasts, as demonstrated by in vitro incubation techniques; in vivo studies suggest that concentration in phagocytes may contribute to drug distribution to inflamed tissues Y-site: Amikacin, aztreonam, cefotaxime, ceftazidime, ceftriaxone, cefuroxime, ciprofloxacin, clindamycin, droperidol, famotidine, fentanyl, furosemide, gentamicin, imipenem, cilastatin, ketorolac, levofloxacin, morphine, piperacillin-tazobactam, ondansetron(? ), potassium chloride, ticarcillin-clavulanate, tobramycin The above information is provided for general informational and educational purposes only. Individual plans may vary and formulary information changes. Contact the applicable plan provider for the most current information. ) Azithromycin is an azalide antibiotic related to erythromycin. Prenatal prescription of macrolide antibiotics and infantile hypertrophic pyloric stenosis. Molecular weight: 749.0 "Reproduction studies have been performed in rats and mice at doses up to moderately maternally toxic dose concentrations (i.e., 200 mg/kg/day). These doses, based on a mg/m 2 basis, are estimated to be 4 and 2 times, respectively, the human daily dose of 500 mg. In the animal studies, no evidence of harm to the fetus due to azithromycin was found."  Azithromycin appears to have limited transplacental transfer  in humans with high sustained levels within myometrium, adipose, and placental tissue . Maternal and infant use of erythromycin and other macrolide antibiotics as risk factors for infantile hypertrophic pyloric stenosis. Reports on the use of azithromycin during the first trimester in human pregnancy are scarce. The preponderance of the literature describes the use of azithromycin during the second and third trimesters of pregnancy. In an observational study of newly marketed drugs prescribed in England azithromycin was taken during the first trimester in eleven pregnancies. The remaining mothers delivered ten normal infants . Ogasawara KK and Goodwin TM Efficacy of azithromycin in reducing lower genital Ureaplasma urealyticum colonization in women at risk for preterm delivery. Propranolol user reviews Levitra efficacy Cost comparison viagra cialis levitra Pregnancy Considerations Adverse events were not observed in animal studies; therefore, azithromycin is classified as pregnancy category B. Azithromycin crosses the placenta. Fetal malformations have not been observed following maternal use of azithromycin. Pregnancy. There are no adequate data from the use of azithromycin in pregnant women. In reproduction toxicity studies in animals azithromycin was shown to pass the placenta, but no teratogenic effects were observed see section 5.3. The safety of azithromycin has not been confirmed with regard to the use of the active substance during pregnancy. Azithromycin except Zmax can be taken with or without food, but food reduces stomach upset. Zmax should be taken on an empty stomach 1 hour before or 2 hours after a Generic Name: azithromycin (a ZITH roe MYE sin)Brand Names: Azasite, Azithromycin 3 Day Dose Pack, Azithromycin 5 Day Dose Pack, Zithromax, Zithromax TRI-PAK, Zithromax Z-Pak, Zmax Medically reviewed by Sophia Entringer, Pharm D. Azithromycin is an antibiotic that fights bacteria. Azithromycin is used to treat many different types of infections caused by bacteria, such as respiratory infections, skin infections, ear infections, eye infections, and sexually transmitted diseases. Azithromycin may also be used for purposes not listed in this medication guide. You should not use azithromycin if you have ever had jaundice or liver problems when you have previously taken this medicine. You should not use azithromycin if you are allergic to it, or if: This medicine is not expected to harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant. It is not known whether azithromycin passes into breast milk or if it could harm a nursing baby. Take azithromycin exactly as prescribed by your doctor. Do not take this medicine in larger or smaller amounts or for longer than recommended. Azithromycin belongs to the family of medications known as macrolide antibiotics. It is used to treat certain types of infections that are caused by bacteria. It is most commonly used to treat ear infections (e.g., otitis media), throat infections, lung infections (e.g., pneumonia), certain sexually transmitted infections, and skin infections. It can also be used to prevent mycobacterium avium complex (MAC) infections in people with HIV infection and to treat flare-ups of chronic obstructive pulmonary disease (COPD) caused by bacteria. Your doctor may have suggested this medication for conditions other than the ones listed in these drug information articles. If you have not discussed this with your doctor or are not sure why you are being given this medication, speak to your doctor. Do not stop using this medication without consulting your doctor. Azithromycin pregnant Antibiotics and pregnancy What's safe? - Mayo Clinic, Azithromycin 500mg Tablets - Medicines Metformin vitamin b12 deficiency Therefore azithromycin in pregnancy and cure chlamydia during pregnancy. Diet during pregnancy only if your prescription medicine is. Downloads useful for seven is the egg follicle flushing is annoying. Azithromycin during pregnancy - Incredible Correlation of Medicine.. Azithromycin Zithromax Antibiotic Side Effects. Zithromax Azithromycin Side Effects,. Azithromycin is contraindicated in patients in whom cholestatic jaundice or hepatic dysfunction previously developed when given azithromycin. Use in Special Populations. Azithromycin is Pregnancy Category B. Care should be exercised when azithromycin is given to a breast-feeding woman. WebMD provides important information about Azithromycin Oral such as if you can you take Azithromycin Oral when you are pregnant or nursing or If Azithromycin Oral dangerous for children or adults. Learn which medications are safe to treat chlamydia during pregnancy, as well. for the treatment of chlamydia during pregnancy azithromycin, erythromycin.