Metoprolol is used alone or in combination with other medications to treat high blood pressure. It also is used to prevent angina (chest pain) and to improve survival after a heart attack. Metoprolol also is used in combination with other medications to treat heart failure. Metoprolol is in a class of medications called beta blockers. It works by relaxing blood vessels and slowing heart rate to improve blood flow and decrease blood pressure. High blood pressure is a common condition and when not treated, can cause damage to the brain, heart, blood vessels, kidneys and other parts of the body. Damage to these organs may cause heart disease, a heart attack, heart failure, stroke, kidney failure, loss of vision, and other problems. Absorption: Well absorbed after oral administration. Distribution: Crosses the blood-brain barrier, crosses the placenta; small amounts enter breast milk. Metabolism and Excretion: Mostly metabolized by the liver (primarily by CYP2D6; the CYP2D6 enzyme system exhibits genetic polymorphism); ~7% of population may be poor metabolizers and may have significantly ↑ metoprolol concentrations and an ↑ risk of adverse effects. TIME/ACTION PROFILE (cardiovascular effects)When switching from immediate-release to extended-release product, the same total daily dose can be used PO: (Adults) Antihypertensive/antianginal– 25–100 mg/day as a single dose initially or 2 divided doses; may be ↑ q 7 days as needed up to 450 mg/day (immediate-release) or 400 mg/day (extended-release) (for angina, give in divided doses). MI– 25–50 mg (starting 15 min after last IV dose) q 6 hr for 48 hr, then 100 mg twice daily. Heart failure– 12.5–25 mg once daily (of extended-release), can be doubled every 2 wk up to 200 mg/day. Migraine prevention– 50–100 mg 2–4 times daily (unlabeled). IV: (Adults) MI– 5 mg q 2 min for 3 doses, followed by oral dosing. Tablets (tartrate): 25 mg, 50 mg, 100 mg Cost: Generic: All strengths $7.18/100Extended-release tablets (succinate; Toprol XL): 25 mg, 50 mg, 100 mg, 200 mg Cost: Generic: 25 mg $35.68/100, 50 mg $41.93/100, 100 mg $53.95/100, 200 mg $84.54/100Solution for injection: 1 mg/m LIn Combination with:hydrochlorothiazide (Dutoprol, Lopressor HCT). See combination drugs.metoprolol is a sample topic from the Davis's Drug Guide. Buy phenergan 25mg tablets Prednisone overdose effects NHS medicines information on metoprolol - what it's used for, side effects, dosage. There are some medicines that may interfere with the way metoprolol works. I was having trouble with the metoprolol tartrate, which seemed to work for a few hours, then my heart rate would go up the rest of the day. Find out more about what is metoprolol, how to take metoprolol safely. Beta-blockers work by blocking some natural chemicals in the body. Added : I just recently started taking my 50mg dose at night like my MD recommended and then monitor my BP and HR during the day to make sure its still effective in keeping them within normal ranges. Added : The medications I take in the morning are lexapro 20mg and Vyvanse 60mg. metoprolol adds to the CNS effects of psych meds, so I agree that you should try taking it at night. Matter of fact, before bed may actually help you get to sleep better. Now, you may want to consider that some folks experience urinary incontinence with metoprolol and if you have a tendency to have to go at night more than during the day, this may be something to watch as you try it out. God bless you, please let me know if I could be of any assistance? I take it also, as needed, for back pain and I notice that if I take it a couple of days in a row, I start getting that last minute urge/now it's too late kind of thing that goes away when I have a break in dosing. I used to take 100mg SR at night, my doctor now has prescribed me to take it once in the morning too - Metoproplol 100mg SR capsules. So if I switch to taking the metoprolol which is the extended release version at night rather than with my anti-depressants and vyvanse in the morning, will it still be effective in controlling my BP and Tachycardia symptoms during the day as well. I guess the only way to know for sure is to take my vitals throughout the day to see. jbacon - I am interested in hearing a bit about your experience. Notes: In general, seniors or children, people with certain medical conditions (such as liver or kidney problems, heart disease, diabetes, seizures) or people who take other medications are more at risk of developing a wider range of side effects. For a complete list of all side effects, click here. Metoprolol is a selective beta-blocker at dosages usually prescribed to lower blood pressure or relieve the symptoms of angina. Two different salts are available, metoprolol tartrate and metoprolol succinate. Metoprolol how does it work Metoprolol Lopressor or Toprol XL - Know Your Drug - YouTube, Is it better to take Metoprolol in the morning or at night. Buy xenical in south africaBuy cialis australia paypalSafest place to buy kamagraValacyclovir how long does it take to workBuy stromectol ivermectin Learn how beta-blocking TOPROL-XL® metoprolol succinate Extended Release Tablets work. How Does TOPROL-XL® metoprolol succinate Work?. Metoprolol Health Navigator NZ. How Does Metoprolol Succinate Treat Ischemic Heart Disease?. How does metoprolol work? Metoprolol is a type of medicine called a beta-blocker. These medicines work by blocking beta receptors that are. Metoprolol answers are found in the Davis's Drug Guide powered by. Does not usually affect beta2 pulmonary, vascular, uterine-adrenergic receptor sites. You should not use this medication if you are allergic to metoprolol, or if you have a serious heart problem such as heart block, sick sinus syndrome, or slow.